Taiza H Figueiredo Selected Research

Nerve Agents

12/2020	Acetylcholinesterase inhibitors (nerve agents) as weapons of mass destruction: History, mechanisms of action, and medical countermeasures.
11/2020	Electroencephalographic analysis in soman-exposed 21-day-old rats and the effects of midazolam or LY293558 with caramiphen.
1/2020	Targeting the glutamatergic system to counteract organophosphate poisoning: A novel therapeutic strategy.
10/2018	Full Protection Against Soman-Induced Seizures and Brain Damage by LY293558 and Caramiphen Combination Treatment in Adult Rats.
10/2018	Acute and long-term consequences of exposure to organophosphate nerve agents in humans.
1/2018	Comparing the Antiseizure and Neuroprotective Efficacy of LY293558, Diazepam, Caramiphen, and LY293558-Caramiphen Combination against Soman in a Rat Model Relevant to the Pediatric Population.
11/2017	Susceptibility to Soman Toxicity and Efficacy of LY293558 Against Soman-Induced Seizures and Neuropathology in 10-Month-Old Male Rats.
1/2016	Long-term neuropathological and behavioral impairments after exposure to nerve agents.
4/2015	A rat model of nerve agent exposure applicable to the pediatric population: The anticonvulsant efficacies of atropine and GluK1 antagonists.
2/2015	LY293558 prevents soman-induced pathophysiological alterations in the basolateral amygdala and the development of anxiety.

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Taiza H Figueiredo Research Topics

Disease

17	Status Epilepticus (Complex Partial Status Epilepticus) 12/2020 - 01/2010
16	Seizures (Absence Seizure) 11/2020 - 09/2009
2	Body Weight (Weight, Body) 10/2018 - 11/2017
1	Tremor (Tremors) 10/2018
1	Rhinorrhea 10/2018
1	Miosis 10/2018
1	Anxiety Disorders (Anxiety Disorder) 01/2018
1	Brain Concussion (Cerebral Concussion) 01/2018
1	Chronic Disease (Chronic Diseases) 01/2018
1	Contusions 01/2018
1	Atrophy 01/2018
1	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2015
1	Cognitive Dysfunction 11/2015
1	Mental Disorders (Mental Disorder) 02/2014
1	Respiratory Insufficiency (Respiratory Failure) 01/2013
1	Epilepsy (Aura) 02/2011
1	Pain (Aches) 02/2011

Drug/Important Bio-Agent (IBA)

17	Nerve AgentsIBA 12/2020 - 09/2009
11	SomanIBA 11/2020 - 09/2010
8	tezampanelIBA 11/2020 - 02/2011
6	Diazepam (Valium)FDA LinkGeneric 12/2020 - 01/2010
6	AcetylcholinesteraseIBA 01/2020 - 09/2013
5	Anticonvulsants (Antiepileptic Drugs)IBA 12/2020 - 01/2013
3	Midazolam (Versed)FDA LinkGeneric 12/2020 - 01/2020
3	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 01/2020 - 11/2015
3	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2020 - 11/2015
2	BenzodiazepinesIBA 12/2020 - 01/2018
2	caramiphenIBA 11/2020 - 10/2018
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 11/2020 - 11/2015
2	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 11/2020 - 02/2011
2	OrganophosphatesIBA 01/2020 - 01/2017
2	Atropine FDA LinkGeneric 04/2015 - 01/2013
2	Kainic Acid Receptors (Kainate Receptor)IBA 11/2014 - 02/2011
2	Carboxylic AcidsIBA 01/2013 - 02/2011
2	AcidsIBA 01/2013 - 02/2011
2	1H-tetrazole (tetrazole)IBA 01/2013 - 02/2011
1	Neuroprotective AgentsIBA 12/2020
1	Muscarinic AntagonistsIBA 11/2020
1	alpha-Linolenic Acid (Linolenic Acid)IBA 01/2018
1	Muscarinic M1 ReceptorIBA 01/2017
1	N- (3- oxo- 3- (4- (pyridin- 4- yl)piperazin- 1- yl)propyl)benzo(c)(1,2,5)thiadiazole- 4- sulfonamideIBA 01/2017
1	willardiineIBA 11/2014
1	1- (2- amino- 2- carboxyethyl)- 3- (2- carboxybenzyl)pyrimidine- 2,4- dioneIBA 11/2014
1	Acid Sensing Ion ChannelsIBA 02/2014
1	OximesIBA 01/2013
1	AMPA Receptors (AMPA Receptor)IBA 01/2013
1	asoxime chloride (H16)IBA 01/2013
1	Kainic Acid (Kainate)IBA 02/2011
1	fluoro-jade CIBA 09/2010
1	GABA-A Receptors (GABA(A) Receptor)IBA 01/2010

Therapy/Procedure

2	Therapeutics 01/2018 - 11/2015
1	Emergency Treatment 02/2011